可以用互斥.
using System.Runtime.InteropServices;
#region 让程序只能运行一次
/// <summary>
/// 让程序只能运行一次
/// </summary>
[StructLayout(LayoutKind.Sequential)]
public class SECURITY_ATTRIBUTES
{
public int nLength;
public int lpSecurityDescriptor;
public int bInheritHandle;
}
[System.Runtime.InteropServices.DllImport("kernel32")]
private static extern int GetLastError();
[System.Runtime.InteropServices.DllImport("kernel32")]
private static extern IntPtr CreateMutex(SECURITY_ATTRIBUTES lpMutexAttributes, bool bInitialOwner, string lpName);
[System.Runtime.InteropServices.DllImport("kernel32")]
private static extern int ReleaseMutex(IntPtr hMutex);
const int ERROR_ALREADY_EXISTS = 0183;