No, anti-aliasing doesn't work with 8-bpp. If you need faster updates, consider doing your drawing with something like OpenGL instead of via GDI. With OpenGL, the drawing will normally be done entirely by the graphics hardware, so even at 32-bpp, the drawing will usually be faster than GDI doing 8-bpp.
It's also worth noting that you'd probably be better off with 32-bpp than either 8- or 24-bpp in any case. GDI can use (some) hardware acceleration, but it's usually at its best with 32-bpp.
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